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Generic Acomplia

The European Medicines Agency (EMEA) has recommended the suspension of EU marketing authorisation of Sanofi-Aventis´ anti-obesity drug Acomplia (rimonabant). The body's Committee for Medicinal Products for Human Use (CHMP) concluded the treatment's benefits no longer outweighed its risks.

Acomplia Usage

Acomplia (Zimulti / Rimonabant) is used in the treatment of obesity and related conditions.
It acts by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism, including adipose tissue, the liver, gastrointestinal tract and muscle. Acomplia switches off the same brain circuits that make people hungry when they smoke cannabis.

How to take acomplia

Use as directed by doctor. However, doses consist of one tablet taken orally every day before breakfast.
It should be swallowed with a full glass of water.

Acomplia side effects

Side effects in trials on Acomplia were vomiting and nausea.

Precaution

Acomplia should only be used with patients who have a BMI over 30 or a BMI over 27 with associated risk factors. Do not take while on anti-depressive medication. Acomplia should be cautiously in patients with moderate renal impairment, epilepsy, patients using potent inhibitors and rare hereditary disorders and galactose intolerance. In addition those over 75 should take care when using the Acomplia. Those who should not take Acomplia include those with severe renal impairment, uncontrolled psychological disorders, a cardiovascular event in the last six months and patients who are breastfeeding or pregnant.

Acomplia drug interactions

Inform your doctor about all the medicines you use, (prescription and nonprescription) especially if you take: high blood pressure medicine, MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), any other weight loss medicine. Avoid "stimulant" drugs that may increase your heart rate such as decongestants or caffeine. Decongestants are commonly found in over-the-counter cough-and-cold medicines. Do not start or stop any medicine without doctor or pharmacist approval.

Missed dose

Take any missed dose as soon as possible but not if it is within 8 hours of the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not "double-up" the dose.

Storage

Store at room temperature and keep away from moisture and sunlight. Do not store in the bathroom.

 

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